Artificial intelligence improves estimation of tacrolimus area under the concentration over time curve in renal transplant recipients

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Clinical Pharmacokinetics of Tacrolimus in Iranian Liver Transplant Recipients

Tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. To date, there is no information on the pharmacokinetics of tacrolimus in Iranian liver transplant recipients. This study was designed to determine pharmacokinetic properties of orally administe...

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Tacrolimus has become an important cornerstone in the prevention of rejection after kidney transplantation. However, its use has been complicated by several side effects, including chronic allograft nephropathy, diabetes mellitus, arterial hypertension, and neurotoxicity. Tacrolimus-induced neutropenia is a less recognized, but potentially harmful complication. Three patients with severe neutro...

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Clinical Pharmacokinetics of Tacrolimus in Iranian Liver Transplant Recipients

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ژورنال

عنوان ژورنال: Transplant International

سال: 2018

ISSN: 0934-0874

DOI: 10.1111/tri.13271